Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes After Zinc and Anti-oxidant Therapy
نویسنده
چکیده
AIM To assess serum Cu/Zn SOD (Superoxide Dismutase) concentration in individuals with clinical depression. SUBJECTS AND METHODS Serum from 36 individuals diagnosed with clinical depression and 18 healthy controls were tested for Cu/Zn SOD serum concentration using ELISAs. RESULTS Serum Cu/Zn SOD levels of depressed individuals (both with and without secondary anxiety) were significantly higher than age and gender similar controls. We also found that, post anti-oxidant therapy, Cu/Zn SOD levels normalized to the level of normal healthy controls. DISCUSSION These results suggest an association between Cu/Zn SOD serum levels and clinical depression.
منابع مشابه
Analysis of Plasma Zinc and Copper Concentration, and Perceived Symptoms, in Individuals with Depression, Post Zinc and Anti-Oxidant Therapy
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